Efficacy and tolerability of urate lowering drugs in gout: a randomised controlled trial of benzbrom
OBJECTIVES: To investigate the efficacy and tolerability of allopurinol as first-choice antihyperuricemic treatment for gout, and compare the efficacy and tolerability of benzbromarone and probenecid as second-choice treatment. METHODS: Prospective, multi-centre, open-label, randomised controlled trial of gout patients with normal renal function. Patients were given 300 mg allopurinol for 2 months (stage 1). When allopurinol was not tolerated or failed to attain target serum urate concentrations (sUr)
Groningen, The Netherlands
The Netherlands
Departments Name: Department of Pharmacotherapy and Pharmaceutical Care
Institution name: University of Groningen
Authors: Reinders MK, van Roon EN, Jansen TL, Delsing J, Griep EN, Hoekstra M, van de Laar MA, Brouwers JR.
Journal Name: Ann Rheum Dis.
Data: 2008, Apr 23
Country: The Netherlands
Other Categories:
 Gout
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