Renal Cell Carcinoma

[Human chromosome 3P regions of putative tumor-suppressor genes in renal, breast, and ovarian carcin
Allelic imbalances (AI) of polymorphic markers at the short arm of chromosome 3 (3p) were mapped using DNA samples of renal cell carcinoma (RCC, 80 cases), breast carcinoma (BC, 95 cases), and epithelial ovarian cancer (EOC, 50 cases) at the same dense panel of markers (up to 24 loci).


Russia
An adjuvant autologous therapeutic vaccine (HSPPC-96; vitespen) versus observation alone for patient
BACKGROUND: Treatment of localised renal cell carcinoma consists of partial or radical nephrectomy.

Houston, TX
USA
Activation of PI3K is associated with reduced survival in renal cell carcinoma
OBJECTIVES: The epidermal growth factor receptor- (EGFR) activated phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB/Akt) pathway is associated with tumorigenesis and progression.

Tubingen, Germany
Germany
Cytokine therapy response as a selection criterion for cytoreductive nephrectomy in metastatic renal
AIMS: To assess the strategy of using an absence of progression at metastatic sites following initial cytokine therapy outcome as a selection criterion for nephrectomy in patients with synchronous metastatic renal carcinoma and an intermediate prognosis according to the Memorial Sloan Kettering prognostic index classification.

Amsterdam, The Netherlands
The Netherlands
[Current aspects in the therapy of renal cell cancer]
The nephron-sparing partial nephrectomy has become the gold standard in the surgical therapy of small renal tumors (4-7 cm).

Halle, Denmark
Denmark
Global analysis of metastasis-associated gene expression in primary cultures from clinical specimens
Metastatic clear-cell renal-cell carcinoma (ccRCC) has a poor prognosis and unpredictable course, and there are no molecular markers that reliably predict ccRCC metastasis.

Shanghai, China
China
A three-gene expression signature model to predict clinical outcome of clear cell renal carcinoma
Renal cell carcinomas (RCCs) are morphologically and genetically heterogeneous tumors and present diverse clinical courses.

Yokohama, Japan
Japan
Laparoscopic partial nephrectomy in the treatment of renal cell carcinoma: a minimally invasive mean
With the advent of cross-sectional imaging, the incidence of asymptomatic detected small renal masses, 'incidentalomas', has increased in the past 20 years.

New York, NY
USA
Immunotherapy for renal cell cancer in the era of targeted therapy
Until recently, cytokine therapy has been the only validated option for patients with advanced renal cancer.

Vancouver,
Canada
Molecular genetics of hereditary renal cancer: new genes and diagnostic and therapeutic opportunitie
Renal cell carcinoma may be sporadic or occur in the setting of an inherited cancer syndrome, such as von Hippel-Lindau or Birt-Hogg-Dube syndrome.
9500 Euclid Avenue, Desk L25
Cleveland, OH 44195
USA