Ovarian Cancer

[Evidence and issues in standardization of intraperitoneal chemotherapy]
Intraperitoneal (i.p.) chemotherapy targets i.p. regional metastasis by maintenance of high-dose intensity.

Yokohama, Japan
Japan
Trichostatin A up-regulates p73 and induces Bax-dependent apoptosis in cisplatin-resistant ovarian c
Several studies in the last years evidenced that deregulation of proapoptotic and antiapoptotic pathways are key players in the onset and maintenance of chemoresistance in advanced ovarian cancers.
Via dei sardi 70
Rome, Italy 00185
Italy
[Importance of chromosomal changes correlated to prognostic factors in ovarian and cervical malignan
OBJECTIVE: The aim of the study was to estimate genetic changes detected in ovarian and cervical cancer cells, in correlation with other available clinical and histopathological parameters, with impact upon cancer prognosis.

Brno, Czech Republic
Czech Republic
Nanoparticle delivery of suicide DNA for epithelial ovarian cancer therapy
Intraperitoneal administration of polymeric nanoparticles to deliver DNA encoding suicide genes holds much promise as an effective therapy for advanced epithelial ovarian cancer.


USA
The promise and perils of 'targeted therapy' of advanced ovarian cancer
For several reasons, ovarian cancer is an excellent malignancy to consider the use of 'targeted' therapeutic strategies.

Houston, TX 77030
USA
Role of diaphragmatic surgery in 69 patients with ovarian carcinoma
Diaphragmatic stripping or coagulation is a technique aiming to optimally cytoreduce ovarian cancer.

Leuven, The Netherlands
The Netherlands
A phase II, multicenter trial of weekly topotecan in patients with recurrent platinum-sensitive epit
The purpose of this study was to evaluate the response rate and toxicity of weekly topotecan in patients with recurrent platinum-sensitive epithelial cancers of the ovary and peritoneum.

Newport Beach, CA 92663
USA
Randomized phase 3 trial of interferon gamma-1b plus standard carboplatin/paclitaxel versus carbopla
OBJECTIVES: Interferon gamma (IFN-gamma) is a pleiotropic cytokine with antiproliferative, immunostimulatory, and chemosensitization properties.

Tucson, AZ
USA
Review: intracavitary radioimmunotherapy to treat solid tumors
Radioimmunotherapy (RIT) potentially is an attractive treatment for radiosensitive early-stage solid tumors and as an adjuvant to cytoreductive surgery.

Nijmegen, The Netherlands
The Netherlands
Aggressive surgical strategies in advanced ovarian cancer: A monocentric study of 203 stage IIIC and
AIMS: The standard treatment for advanced ovarian cancer consists of cytoreductive surgery associated with a platinum/paclitaxel-based chemotherapy.
208 rue des Apothicaires, 34298 Montpellier Cedex 5

France