Herpes

The high prevalence of herpes simplex virus type 1 DNA in human trigeminal ganglia is not a function
The purpose of this study was to determine the presence and copy numbers of herpes simplex virus type 1 (HSV-1) DNA in human trigeminal ganglia (TG) with respect to age, gender, and postmortem interval (PMI). Human TG (n = 174, obtained from the Oregon Brain Bank, with data on age, gender, and PMI) were analyzed for HSV-1 DNA copies (HSV-1 DNA polymerase gene) by using real-time PCR.

New Orleans, LA
USA
Herpes simplex virus and HIV-1: deciphering viral synergy
Recent proof-of-concept randomised controlled trials have shown a causal relation between herpes simplex virus (HSV) type 2 infection and HIV-1 replication in co-infected individuals.

Montpellier, France
France
The treatment of herpes simplex infections: an evidence-based review
Genital and labial herpes simplex virus infections are frequently encountered by primary care physicians in the United States.

Rootstown, OH
USA
Recent advances in management of genital ulcer disease and anogenital warts
Genital ulcer disease (GUD) constitutes a major public health problem.

Pondicherry, India
India
Herpes simplex virus helicase-primase inhibitors: recent findings from the study of drug resistance
After several decades during which nucleoside analogues (especially acyclovir and penciclovir and their prodrugs) have benefited many patients suffering from herpes simplex virus (HSV) infections, the discovery of the helicase-primase inhibitors (HPIs) represents an interesting new approach.

Cambridge, UK
UK
One-Day Regimen of Valacyclovir for Treatment of Recurrent Genital Herpes Simplex Virus 2 Infection
OBJECTIVES:: To evaluate the efficacy of a 1-day course of valacyclovir in reducing the duration and severity of genital herpes recurrences and to measure the frequency of viral shedding episodes subsequent to antiviral therapy.

Seattle, Washington; North Carolina; Houston, TX; Portland, Oregon,
USA
Condoms for sexually transmissible infection prevention: politics versus science
The present review assesses the protection that condoms offer against sexually transmissible infections (STI) and the impact that social, political and religious opinion in the USA has had in the past 8 years on promoting condoms for safer sex.

Sydney, Australia
Australia
Clinical and Laboratory Features of Neonatal Herpes Simplex Virus Infection: A Case-Control Study
BACKGROUND:: Neonatal herpes simplex virus (HSV) infection can cause significant morbidity and mortality but can be difficult to identify, particularly in neonates without vesicular rash.

Houston, TX
USA
Treatment of herpes zoster
OBJECTIVE: To review the evidence regarding treatment of herpes zoster (HZ) in the short-term, focusing on the prevention of postherpetic neuralgia (PHN).

Utrecht, The Netherlands
The Netherlands
Preventing herpes zoster through vaccination
TOPIC: The role of the zoster vaccine in the prevention of herpes zoster and its sequelae, including postherpetic neuralgia (PHN) and herpes zoster ophthalmicus.

St. Louis, MO 63110
USA