Gastroesophageal Reflux

Synthesis and pharmacological evaluation of novel gamma-aminobutyric acid type B (GABAB) receptor ag
We have previously demonstrated that the prototypical GABA B receptor agonist baclofen inhibits transient lower esophageal sphincter relaxations (TLESRs), the most important mechanism for gastroesophageal reflux.

Mölndal, Sweden
Sweden
Mechanisms of heartburn
Heartburn is a typical symptom of GERD.
Herestraat 49
Leuven, Belgium
The Netherlands
Non-erosive and erosive gastroesophageal reflux diseases: No difference with regard to reflux patter
OBJECTIVE: To investigate whether gastroesophageal reflux disease (GERD) with mild to moderate erosive esophagitis (ERD) is a more severe disease regarding the amount of acid reflux, motor abnormalities, and the presence/absence of hiatus hernia than non-erosive reflux disease (NERD).

Prague, Czech Republic
Czech Republic
Relationship of severity of gastroesophageal reflux disease with gastric acid secretory profile and
OBJECTIVE: In patients with gastroesophageal reflux disease (GERD), refluxed gastric juice can damage the esophagus, and hence the more acidic the juice, the more the expected damage.

Lucknow, India
India
Airway acidification and gastroesophageal reflux
Although challenging to study, researchers recently recognized the relevance of airway pH to the pathophysiology of several respiratory diseases, ranging from asthma and cystic fibrosis to pneumonia.
Box 800386
Charlottesville, VA 22908
USA
Clinical response to 2 dosing regimens of lansoprazole in infants with gastroesophageal reflux
Proton pump inhibitors such as lansoprazole are used in the treatment of gastroesophageal reflux disease (GERD), but dosing guidelines for infants have not been determined.
1111 Medical Center Blvd, South 650
Marrero, LA 70072
USA
Efficacy of conservative therapy as taught in the primary care setting for symptoms suggesting infan
OBJECTIVE: To determine the efficacy of non-pharmacologic conservative therapy for infant gastroesophageal reflux disease (GERD).

Pittsburgh, PA
USA
Systematic review; gastroesophageal reflux disease and dental lesions
Background: Dental erosion (DE), which is the irreversible loss of tooth substance that does not involve bacteria ranging from a minimal loss of surface enamel to the partial or complete exposure of dentin by a chemical process, is acknowledged as an established extraesophageal manifestation of Gastroesophageal reflux (GERD).

Milan, Italy
Italy
Laparoscopic Revisional Fundoplication with Circular Hiatal Mesh Prosthesis: The Long-term Results
BACKGROUND: Failure of hiatal closure has proven to be the most frequent complication leading to revisional surgery after primary failed open or laparoscopic antireflux surgery.
Hoppe-Seyler-Strasse 3
Tubingen, Germany 72076
Germany
Recent Advances in the Surgical Treatment of Achalasia and Gastroesophageal Reflux Disease
Achalasia and gastroesophageal reflux disease (GERD) represent diverse physiologic disorders both of which result from lower esophageal sphincter (LES) dysfunction.

New Haven, CT
USA