Breast Cancer

A central role for HER3 in HER2-amplified breast cancer: implications for targeted therapy
Epidermal growth factor receptor (EGFR) and HER3 each form heterodimers with HER2 and have independently been implicated as key coreceptors that drive HER2-amplified breast cancer.

San Francisco, CA 94080
USA
Results of the first phase I clinical trial of the novel II-key hybrid preventive HER-2/neu peptide
PURPOSE: HER-2/neu is overexpressed in breast cancer and is the source of immunogenic peptides.
3851 Roger Brooke Dr
Houston, TX 78234
USA
Design, synthesis, and evaluation of novel mutual prodrugs (hybrid drugs) of all-trans-retinoic acid
Novel mutual prodrugs (MPs) of ATRA (all- trans-retinoic acid) and HDIs (histone deacetylase inhibitors) ( 10, 13, 17- 19) connected via glycine acyloxyalkyl carbamate linker (AC linker) or through a benzyl ester linker (1,6-elimination linker) were rationally designed and synthesized.
685 West Baltimore Street
Baltimore, MD 21201-1559
USA
Polygenes, risk prediction, and targeted prevention of breast cancer
BACKGROUND: New developments in the search for susceptibility alleles in complex disorders provide support for the possibility of a polygenic approach to the prevention and treatment of common diseases.


UK
[Dual effects of androgens on mammary gland]
Androgens have a dual effect on mammary cells.
1, place de l'Hôpital, 67091 Strasbourg

France
"Stemness" genomics law governs clinical behavior of human cancer: implications for decision making
One of the most significant accomplishments of translational oncogenomics is a realistic promise of efficient diagnostic tests that would facilitate implementation of the concept of individualized cancer therapies.
150 New Scotland Ave.
Albany, NY 12208
USA
"Stemness" genomics law governs clinical behavior of human cancer: implications for decision making
One of the most significant accomplishments of translational oncogenomics is a realistic promise of efficient diagnostic tests that would facilitate implementation of the concept of individualized cancer therapies.
PO Box 2900
Durham, NC 27710
USA
Implications of the cancer stem-cell hypothesis for breast cancer prevention and therapy
Recent research in breast biology has provided support for the cancer stem-cell hypothesis.

Ann Arbor, MI 48109-5942
USA
Absolute Risk Reductions for Local Recurrence After Postoperative Radiotherapy After Sector Resectio
PURPOSE: Evaluate the effects of radiotherapy after sector resection for ductal carcinoma in situ of the breast (DCIS) in patient groups as defined by age, size of the lesion, focality, completeness of excision and mode of detection.

London, UK
UK
Response to Neoadjuvant Therapy and Long-Term Survival in Patients With Triple-Negative Breast Cance
PURPOSE: Triple-negative breast cancer (TNBC) is defined by the lack of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER-2) expression.

Villejuif, France
France