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Adverse childhood experiences predict earlier age of drinking onset: results from a representative U
OBJECTIVE: Our goal was to determine whether adverse childhood experiences predicted the age at which drinking was initiated and drinking motives in a representative sample of current or former drinkers in the United States.
Boston, Massachusetts 02118 USA Systematic analysis of glutamatergic neurotransmission genes in alcohol dependence and adolescent ri
CONTEXT: Glutamatergic neurotransmission is implicated in alcohol-drinking behavior in animal models.
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London, England SE5 8AF UK CONTEXT: The endogenous cannabinoid system has been implicated in drug addiction in animal models.
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Richmond, VA 23298 USA Residential detoxification: essential for marginalised, severely alcohol- and drug-dependent individ
INTRODUCTION AND AIMS: In an era of health care rationalisation, residential detoxification services catering for drug- and alcohol-dependent homeless people are being closed.
Sydney, Australia Australia BACKGROUND: Disulfiram has demonstrated efficacy in six randomized clinical trials for the treatment of cocaine dependence, but is rarely used in clinical settings because of safety concerns.
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Charleston, South Carolina 29425 USA It is well known that the prevalence of alcohol use disorders is increasing and represents an important health problem worldwide.
Izmir, Turkey Turkey BACKGROUND: Topiramate can improve drinking outcomes via a hypothesized mechanism of facilitating gamma-aminobutyric acid function and inhibiting glutaminergic pathways in the corticomesolimbic system.
Charlottesville, Virginia 22908-0623 USA [Acute alcoholic intoxication in subjects over 75 years of age: a clinical situation far to be uncom
Acute ethylic intoxication (AEI) or alcoholic drunkenness is not only a youth-specific disorder.
France France The efficacy of acamprosate and naltrexone in the treatment of alcohol dependence: a relative benefi
Random controlled trials on the efficacy of naltrexone and acamprosate in the treatment of alcohol dependence were reviewed, using a Relative Benefit (RB) analysis approach.
Middletown, Pennsylvania 17057 USA The effects of levetiracetam on alcohol consumption in alcohol-dependent subjects: an open label stu
The aim of this open-label pilot study was to assess the efficacy and safety of the novel anticonvulsant agent, levetiracetam, for the treatment of alcohol dependence.
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